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Your Personal AI Longevity
Protocol โ€” Built in 60 Seconds

Stop guessing. LongevityOS analyzes your age, health goals, and budget โ€” then generates a ranked, evidence-based protocol from Tier 1 clinical interventions to cutting-edge experimental options.

Build My Protocol โ†’ See the Science
Powered by 400+ peer-reviewed studies ยท Updated monthly ยท Not medical advice
How It Works

From inputs to actionable protocol in 3 steps

01

Enter your profile

Age, sex, current health status, existing supplements, monthly budget. Takes 60 seconds.

02

AI analyzes the evidence

Our model cross-references clinical trials, meta-analyses, and expert protocols to rank interventions by your specific profile.

03

Get your ranked protocol

Evidence tier, cost breakdown, dosing schedule, and drug interaction warnings โ€” all in plain language.

04

Track & iterate

Log your biomarkers. LongevityOS adjusts your protocol as science advances and your data changes.

Evidence Framework

Ranked by evidence quality โ€” not hype

We use a 3-tier evidence framework. Tier 1 interventions have strong clinical backing. We never mix proven and experimental in the same priority bucket.

Tier 1 โ€” Proven

Strong Clinical Evidence

  • Rapamycin (mTOR inhibition) โ€” immune enhancement trials underway
  • Metformin โ€” TAME trial, AMPK activation
  • GLP-1 agonists โ€” cardiovascular + metabolic protection
  • SGLT2 inhibitors โ€” cardiorenal benefit
  • Exercise (zone 2 + resistance) โ€” #1 intervention by evidence
  • Sleep optimization โ€” 7-9h, HRV-guided
Tier 2 โ€” Promising

Solid Data, More Trials Needed

  • NMN / NR (NAD+ precursors) โ€” muscle function in elderly
  • Senolytics (D+Q, Fisetin) โ€” senescent cell clearance
  • Spermidine โ€” autophagy induction
  • Omega-3 high-dose โ€” cardiometabolic
  • Vitamin D3+K2 โ€” bone, immune, CVD
  • Magnesium threonate โ€” cognitive, sleep
Tier 3 โ€” Experimental

Cutting Edge / Early Stage

  • Partial epigenetic reprogramming (Life Biosciences โ€” FDA Phase 1, 2026)
  • Young plasma / plasma exchange
  • Klotho protein (cognitive protection)
  • CAR-T senolytic therapy
  • mRNA longevity vaccines
Live Demo

Build your protocol now

Fill in your profile and get a sample protocol instantly. Full personalization available on paid plans.

Your Personalized Protocol

โš ๏ธ This is educational information, not medical advice. Consult your physician before starting any new protocol.

Research Digest โ€” March 2026

What's happening now in longevity science

Jan 27, 2026 โ€” MIT Technology Review

First Human Partial Reprogramming Trial Cleared by FDA

Life Biosciences begins first-ever human test of epigenetic reprogramming with ER-100 for vision loss. David Sinclair co-founder.

Feb 2026 โ€” MDPI

Rapamycin + Metformin Synergy Validated in New Review

Combined mTOR/AMPK targeting shows additive healthspan benefits in multi-drug longevity regimens. Biomarker-guided dosing emerging.

Dec 2025 โ€” Hone Health

Low-Dose Rapamycin Reduces Biological Age Markers

Preliminary human data shows measurable reduction in aging biomarkers with intermittent low-dose rapamycin protocol (weekly dosing).

2025โ€“2026 โ€” Clinical Trends

GLP-1s Emerge as Longevity Drugs

Beyond weight loss: Ozempic/Wegovy showing cardiovascular, neurological, and metabolic protection far beyond their original indication.

Pricing

Start free. Go deep when you're ready.

Free
$0/mo

Perfect for exploring what's possible

  • 1 protocol per month
  • Tier 1 interventions only
  • Basic evidence summaries
  • Cost estimates
Build Protocol Free
Longevity Coach
$49/mo

Deep personalization + concierge support

  • Everything in Pro
  • Lab work interpretation
  • Weekly protocol review
  • Priority research alerts
  • Telegram AI coach (24/7)
Get Longevity Coach โ†’
FAQ

Common questions

Is this medical advice?

No. LongevityOS provides evidence-ranked educational information based on published research. Always consult your physician before starting any new supplement, medication, or health protocol โ€” especially prescription interventions like rapamycin or metformin.

How is this different from just googling?

Google gives you 10,000 contradictory articles. LongevityOS synthesizes 400+ peer-reviewed studies, weights them by evidence quality, and filters by YOUR specific age, goals, budget, and health conditions. You get a ranked action list โ€” not a research rabbit hole.

How often is the database updated?

Monthly. When significant trials publish (like the Life Biosciences FDA clearance), we update within days. Pro users get instant alerts.

What about drug interactions?

Our Pro tier includes a drug interaction checker. For example: metformin + B12 depletion warning, rapamycin + immunosuppression cautions, and NMN + cancer risk nuances are all flagged.

Can I use this with my doctor?

Yes โ€” and we encourage it. Pro users can export a PDF of their protocol to share with their physician. More doctors are familiar with longevity medicine every year.